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Microglia Express Mu Opioid Receptor: Insights From Transcriptomics and Fluorescent Reporter Mice

Background: Microglia activation contributes to chronic pain and to the adverse effects of opiate use such as analgesic tolerance and opioid-induced hyperalgesia. Both mu opioid receptor (MOR) encoded by Oprm1/OPRM1 gene and toll like receptor 4 (TLR4) have been reported to mediate these morphine ef...

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Detalles Bibliográficos
Autores principales:	Maduna, Tando, Audouard, Emilie, Dembélé, Doulaye, Mouzaoui, Nejma, Reiss, David, Massotte, Dominique, Gaveriaux-Ruff, Claire
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Psychiatry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328486/ https://www.ncbi.nlm.nih.gov/pubmed/30662412 http://dx.doi.org/10.3389/fpsyt.2018.00726

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