CDX2 inhibits the proliferation and tumor formation of colon cancer cells by suppressing Wnt/β-catenin signaling via transactivation of GSK-3β and Axin2 expression

Caudal-related homeobox transcription factor 2 (CDX2), an intestine-specific nuclear transcription factor, has been strongly implicated in the tumourigenesis of various human cancers. However, the functional role of CDX2 in the development and progression of colorectal cancer (CRC) is not well known...

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Detalles Bibliográficos
Autores principales: Yu, Junhui, Liu, Dong, Sun, Xuejun, Yang, Kui, Yao, Jianfeng, Cheng, Chen, Wang, Chunbao, Zheng, Jianbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328578/
https://www.ncbi.nlm.nih.gov/pubmed/30631044
http://dx.doi.org/10.1038/s41419-018-1263-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328578/
https://www.ncbi.nlm.nih.gov/pubmed/30631044
http://dx.doi.org/10.1038/s41419-018-1263-9

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