Mycobacterium tuberculosis virulence inhibitors discovered by Mycobacterium marinum high-throughput screening

High-throughput screening facilities do not generally support biosafety level 3 organisms such as Mycobacterium tuberculosis. To discover not only antibacterials, but also virulence inhibitors with either bacterial or host cell targets, an assay monitoring lung fibroblast survival upon infection was...

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Detalles Bibliográficos
Autores principales: Tükenmez, Hasan, Edström, Isabel, Ummanni, Ramesh, Fick, Stina Berglund, Sundin, Charlotta, Elofsson, Mikael, Larsson, Christer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328581/
https://www.ncbi.nlm.nih.gov/pubmed/30631100
http://dx.doi.org/10.1038/s41598-018-37176-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328581/
https://www.ncbi.nlm.nih.gov/pubmed/30631100
http://dx.doi.org/10.1038/s41598-018-37176-4

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