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Mycobacterium tuberculosis virulence inhibitors discovered by Mycobacterium marinum high-throughput screening
High-throughput screening facilities do not generally support biosafety level 3 organisms such as Mycobacterium tuberculosis. To discover not only antibacterials, but also virulence inhibitors with either bacterial or host cell targets, an assay monitoring lung fibroblast survival upon infection was...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328581/ https://www.ncbi.nlm.nih.gov/pubmed/30631100 http://dx.doi.org/10.1038/s41598-018-37176-4 |