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Gene expression, proteome and calcium signaling alterations in immortalized hippocampal astrocytes from an Alzheimer’s disease mouse model

Evidence is rapidly growing regarding a role of astroglial cells in the pathogenesis of Alzheimer’s disease (AD), and the hippocampus is one of the important brain regions affected in AD. While primary astroglial cultures, both from wild-type mice and from rodent models of AD, have been useful for s...

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Detalles Bibliográficos
Autores principales: Rocchio, Francesca, Tapella, Laura, Manfredi, Marcello, Chisari, Mariangela, Ronco, Francesca, Ruffinatti, Federico Alessandro, Conte, Eleonora, Canonico, Pier Luigi, Sortino, Maria Angela, Grilli, Mariagrazia, Marengo, Emilio, Genazzani, Armando A., Lim, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328590/
https://www.ncbi.nlm.nih.gov/pubmed/30631041
http://dx.doi.org/10.1038/s41419-018-1264-8