RNA inhibitors of nuclear proteins responsible for multiple organ dysfunction syndrome

The development of multiple organ dysfunction syndrome (MODS) following infection or tissue injury is associated with increased patient morbidity and mortality. Extensive cellular injury results in the release of nuclear proteins, of which histones are the most abundant, into the circulation. Circul...

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Detalles Bibliográficos
Autores principales: Urak, Kevin T., Blanco, Giselle N., Shubham, Shambhavi, Lin, Li-Hsien, Dassie, Justin P., Thiel, William H., Chen, Yani, Sonkar, Vijay Kumar, Lei, Beilei, Murthy, Shubha, Gutierrez, Wade R., Wilson, Mary E., Stiber, Jonathan A., Klesney-Tait, Julia, Dayal, Sanjana, Miller, Francis J., Giangrande, Paloma H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328615/
https://www.ncbi.nlm.nih.gov/pubmed/30631065
http://dx.doi.org/10.1038/s41467-018-08030-y

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