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Antisense oligonucleotides targeting angiotensinogen: insights from animal studies
Angiotensinogen (AGT) is the unique substrate of all angiotensin peptides. We review the recent preclinical research of AGT antisense oligonucleotides (ASOs), a rapidly evolving therapeutic approach. The scope of the research findings not only opens doors for potentially new therapeutics of hyperten...
Autores principales: | Wu, Chia-Hua, Wang, Ya, Ma, Murong, Mullick, Adam E., Crooke, Rosanne M., Graham, Mark J., Daugherty, Alan, Lu, Hong S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328882/ https://www.ncbi.nlm.nih.gov/pubmed/30530571 http://dx.doi.org/10.1042/BSR20180201 |
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