Cargando…

TIMP-1 inhibits proliferation and osteogenic differentiation of hBMSCs through Wnt/β-catenin signaling

The present study aimed to evaluate the effect of tissue inhibitor of metalloproteinase-1 (TIMP-1) on the proliferation and osteogenic differentiation potential of human bone marrow-derived MSCs (hBMSCs). hBMSCs with stable TIMP-1 overexpression or TIMP-1 knockdown were generated. Osteogenic differe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liang, Tangzhao, Gao, Wenling, Zhu, Lei, Ren, Jianhua, Yao, Hui, Wang, Kun, Shi, Dehai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328886/ https://www.ncbi.nlm.nih.gov/pubmed/30473539 http://dx.doi.org/10.1042/BSR20181290

Ejemplares similares

TMT-Based Proteomic Explores the Influence of DHEA on the Osteogenic Differentiation of hBMSCs
por: Liang, Xiaonan, et al.
Publicado: (2021)

Overexpression of RPN2 promotes osteogenic differentiation of hBMSCs through the JAK/STAT3 pathway
por: Ni, Ling, et al.
Publicado: (2019)

Concentrated Growth Factors Promote hBMSCs Osteogenic Differentiation in a Co-Culture System With HUVECs
por: Liao, Yunyang, et al.
Publicado: (2022)

Involvement of CB2 signalling pathway in the development of osteoporosis by regulating the proliferation and differentiation of hBMSCs
por: Tian, Feng, et al.
Publicado: (2021)

Identification of potential specific biomarkers and key signaling pathways between osteogenic and adipogenic differentiation of hBMSCs for osteoporosis therapy
por: Wu, Jianjun, et al.
Publicado: (2020)

Naturally-derived protein extract from Gryllus bimaculatus improves antioxidant properties and promotes osteogenic differentiation of hBMSCs
por: Ganguly, Keya, et al.
Publicado: (2021)

DPA promotes hBMSCs osteogenic differentiation by miR-9-5p/ERK/ALP signaling pathway
por: Gao, Xiang, et al.
Publicado: (2022)

TRIB3 inhibits proliferation and promotes osteogenesis in hBMSCs by regulating the ERK1/2 signaling pathway
por: Zhang, Cui, et al.
Publicado: (2017)

Decellularized Disc Hydrogels for hBMSCs tissue-specific differentiation and tissue regeneration
por: Peng, Yizhong, et al.
Publicado: (2021)

Comparison of hIGF-1 Gene Transfection to the hBMSCs and Human Meniscal Fibrochondrocytes
por: Zhang, Haining, et al.
Publicado: (2015)

Estrogen improves the proliferation and differentiation of hBMSCs derived from postmenopausal osteoporosis through notch signaling pathway
por: Fan, Jin-Zhu, et al.
Publicado: (2014)

Ubiquitination of ASCL1 mediates CD47 transcriptional activation of the AKT signaling pathway, and glycolysis promotes osteogenic differentiation of hBMSCs
por: Zhang, Jimei, et al.
Publicado: (2023)

Activating Wnt/β-Catenin Signaling in Osteocytes Promotes Osteogenic Differentiation of BMSCs through BMP-7
por: Zhang, Yining, et al.
Publicado: (2022)

Silencing HIF-1α reduces the adhesion and secretion functions of acute leukemia hBMSCs
por: Zeng, Dong-Feng, et al.
Publicado: (2012)

Optimization of adeno-associated virus (AAV) gene delivery into human bone marrow stem cells (hBMSCs)
por: Yao, Shaomian, et al.
Publicado: (2023)

PHF8 promotes osteogenic differentiation of BMSCs in old rat with osteoporosis by regulating Wnt/β-catenin pathway
por: Pan, Feng, et al.
Publicado: (2022)

CaSR-Mediated hBMSCs Activity Modulation: Additional Coupling Mechanism in Bone Remodeling Compartment
por: Cho, Hyunji, et al.
Publicado: (2020)

Circular RNA hsa_circ_0076690 acts as a prognostic biomarker in osteoporosis and regulates osteogenic differentiation of hBMSCs via sponging miR-152
por: Han, Shijie, et al.
Publicado: (2020)

Coculture of endothelial progenitor cells and mesenchymal stem cells enhanced their proliferation and angiogenesis through PDGF and Notch signaling
por: Liang, Tangzhao, et al.
Publicado: (2017)

TRPM7 Upregulate the Activity of SMAD1 through PLC Signaling Way to Promote Osteogenesis of hBMSCs
por: Hong, Fanfan, et al.
Publicado: (2020)

Downregulation of the LncRNA MEG3 Promotes Osteogenic Differentiation of BMSCs and Bone Repairing by Activating Wnt/β-Catenin Signaling Pathway
por: Liu, Juan, et al.
Publicado: (2022)

TGM2 accelerates migration and differentiation of BMSCs by activating Wnt/β-catenin signaling
por: Liu, Feng, et al.
Publicado: (2023)

Enhanced in vitro biocompatibility and osteogenesis of titanium substrates immobilized with dopamine-assisted superparamagnetic Fe(3)O(4) nanoparticles for hBMSCs
por: Huang, Zhenfei, et al.
Publicado: (2018)

Bone tissue engineering scaffolds with HUVECs/hBMSCs cocultured on 3D-printed composite bioactive ceramic scaffolds promoted osteogenesis/angiogenesis
por: Liu, Xiao, et al.
Publicado: (2022)

Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis
por: Jing, Huan, et al.
Publicado: (2018)

BMSCs alleviate liver cirrhosis by regulating Fstl1/Wnt/β-Catenin signaling pathway
por: Zhangdi, Hanjing, et al.
Publicado: (2023)

Notoginsenoside R1 Promotes Proliferation and Osteogenic Differentiation of hPDLSCs via Wnt/β-Catenin Signaling Pathway
por: Han, Ruiqi, et al.
Publicado: (2022)

TGF-β1 enhanced myocardial differentiation through inhibition of the Wnt/β-catenin pathway with rat BMSCs
por: Lv, Yang, et al.
Publicado: (2020)

Circular RNA CircSLC8A1 contributes to osteogenic differentiation in hBMSCs via CircSLC8A1/miR‐144‐3p/RUNX1 in periprosthetic osteolysis
por: Yang, Boning, et al.
Publicado: (2022)

Correction: Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis
por: Jing, Huan, et al.
Publicado: (2022)

Overexpression of MiR-183/96/182 Triggers Retina-Like Fate in Human Bone Marrow-Derived Mesenchymal Stem Cells (hBMSCs) in Culture
por: Mahmoudian-Sani, Mohammad-Reza, et al.
Publicado: (2019)

Network pharmacology identifies fisetin as a treatment for osteoporosis that activates the Wnt/β-catenin signaling pathway in BMSCs
por: Liang, Guihong, et al.
Publicado: (2023)

Effects of Extracellular Vesicles from Osteogenic Differentiated Human BMSCs on Osteogenic and Adipogenic Differentiation Capacity of Naïve Human BMSCs
por: Wang, Chenglong, et al.
Publicado: (2022)

Low-dose IL-34 has no effect on osteoclastogenesis but promotes osteogenesis of hBMSCs partly via activation of the PI3K/AKT and ERK signaling pathways
por: Xu, Jianxiang, et al.
Publicado: (2021)

Exosomal miR-100-5p inhibits osteogenesis of hBMSCs and angiogenesis of HUVECs by suppressing the BMPR2/Smad1/5/9 signalling pathway
por: Yang, Wu, et al.
Publicado: (2021)

PTHrP Modulates the Proliferation and Osteogenic Differentiation of Craniofacial Fibrous Dysplasia-Derived BMSCs
por: Shen, Lihang, et al.
Publicado: (2023)

SDF-1 induces directional chemotaxis of BMSCs at the intervertebral fusion site and promotes osteogenic differentiation by regulating Wnt/β-catenin in the bone marrow chimera spinal intervertebral fusion mouse model
por: ZHANG, Qiwen, et al.
Publicado: (2022)

Lumican promotes joint fibrosis through TGF‐β signaling
por: Xiao, Dahai, et al.
Publicado: (2020)

ASPH Regulates Osteogenic Differentiation and Cellular Senescence of BMSCs
por: Peng, Hui, et al.
Publicado: (2020)

Inhibiting KCNMA1-AS1 promotes osteogenic differentiation of HBMSCs via miR-1303/cochlin axis
por: Lin, Yuan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_hs0hvrct350l4u5uu0mnh44kcv