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Ascorbic acid improves parthenogenetic embryo development through TET proteins in mice

The TET (Ten-Eleven Translocation) proteins catalyze the oxidation of 5mC (5-methylcytosine) to 5hmC (5-hydroxymethylcytosine) and play crucial roles in embryonic development. Ascorbic acid (Vc, Vitamin C) stimulates the expression of TET proteins, whereas DMOG (dimethyloxallyl glycine) inhibits TET...

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Detalles Bibliográficos
Autores principales: Gao, Wei, Yu, Xianfeng, Hao, Jindong, Wang, Ling, Qi, Minghui, Han, Liang, Lin, Chao, Wang, Dongxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328890/
https://www.ncbi.nlm.nih.gov/pubmed/30567727
http://dx.doi.org/10.1042/BSR20181730