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Ascorbic acid improves parthenogenetic embryo development through TET proteins in mice
The TET (Ten-Eleven Translocation) proteins catalyze the oxidation of 5mC (5-methylcytosine) to 5hmC (5-hydroxymethylcytosine) and play crucial roles in embryonic development. Ascorbic acid (Vc, Vitamin C) stimulates the expression of TET proteins, whereas DMOG (dimethyloxallyl glycine) inhibits TET...
Autores principales: | Gao, Wei, Yu, Xianfeng, Hao, Jindong, Wang, Ling, Qi, Minghui, Han, Liang, Lin, Chao, Wang, Dongxu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328890/ https://www.ncbi.nlm.nih.gov/pubmed/30567727 http://dx.doi.org/10.1042/BSR20181730 |
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