Chronic treatment with N‐acetylcysteine decreases extinction responding and reduces cue‐induced nicotine‐seeking

N‐acetylcysteine (NAC), a promising glutamatergic therapeutic agent, has shown some clinical efficacy in reducing nicotine use in humans and has been shown to reverse drug‐induced changes in glutamatergic neurophysiology. In rats, nicotine‐seeking behavior is associated with alterations in glutamate...

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Detalles Bibliográficos
Autores principales: Powell, Gregory L., Leyrer‐Jackson, Jonna M., Goenaga, Julianna, Namba, Mark D., Piña, Jose, Spencer, Sade, Stankeviciute, Neringa, Schwartz, Danielle, Allen, Nicholas P., Del Franco, Armani P., McClure, Erin A., Olive, Michael Foster, Gipson, Cassandra D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328917/
https://www.ncbi.nlm.nih.gov/pubmed/30632301
http://dx.doi.org/10.14814/phy2.13958

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