Twik‐2(−/−) mouse demonstrates pulmonary vascular heterogeneity in intracellular pathways for vasocontractility

We have previously shown Twik‐2(−/−) mice develop pulmonary hypertension and vascular remodeling. We hypothesized that distal pulmonary arteries (D‐PAs) of the Twik‐2(−/−) mice are hypercontractile under physiological venous conditions due to altered electrophysiologic properties between the conduit...

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Detalles Bibliográficos
Autores principales: Kitagawa, Melanie G., Reynolds, Julia O., Durgan, David, Rodney, George, Karmouty‐Quintana, Harry, Bryan, Robert, Pandit, Lavannya M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328926/
https://www.ncbi.nlm.nih.gov/pubmed/30632293
http://dx.doi.org/10.14814/phy2.13950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328926/
https://www.ncbi.nlm.nih.gov/pubmed/30632293
http://dx.doi.org/10.14814/phy2.13950

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