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RGS9‐2 rescues dopamine D2 receptor levels and signaling in DYT1 dystonia mouse models
Dopamine D2 receptor signaling is central for striatal function and movement, while abnormal activity is associated with neurological disorders including the severe early‐onset DYT1 dystonia. Nevertheless, the mechanisms that regulate D2 receptor signaling in health and disease remain poorly underst...
Autores principales: | Bonsi, Paola, Ponterio, Giulia, Vanni, Valentina, Tassone, Annalisa, Sciamanna, Giuseppe, Migliarini, Sara, Martella, Giuseppina, Meringolo, Maria, Dehay, Benjamin, Doudnikoff, Evelyne, Zachariou, Venetia, Goodchild, Rose E, Mercuri, Nicola B, D'Amelio, Marcello, Pasqualetti, Massimo, Bezard, Erwan, Pisani, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328939/ https://www.ncbi.nlm.nih.gov/pubmed/30552094 http://dx.doi.org/10.15252/emmm.201809283 |
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