Loss of the mitochondrial i‐AAA protease YME1L leads to ocular dysfunction and spinal axonopathy

Disturbances in the morphology and function of mitochondria cause neurological diseases, which can affect the central and peripheral nervous system. The i‐AAA protease YME1L ensures mitochondrial proteostasis and regulates mitochondrial dynamics by processing of the dynamin‐like GTPase OPA1. Mutatio...

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Detalles Bibliográficos
Autores principales: Sprenger, Hans‐Georg, Wani, Gulzar, Hesseling, Annika, König, Tim, Patron, Maria, MacVicar, Thomas, Ahola, Sofia, Wai, Timothy, Barth, Esther, Rugarli, Elena I, Bergami, Matteo, Langer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328943/
https://www.ncbi.nlm.nih.gov/pubmed/30389680
http://dx.doi.org/10.15252/emmm.201809288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328943/
https://www.ncbi.nlm.nih.gov/pubmed/30389680
http://dx.doi.org/10.15252/emmm.201809288

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