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GMP-compatible and xeno-free cultivation of mesenchymal progenitors derived from human-induced pluripotent stem cells

BACKGROUND: Human mesenchymal stem cells are a strong candidate for cell therapies owing to their regenerative potential, paracrine regulatory effects, and immunomodulatory activity. Yet, their scarcity, limited expansion potential, and age-associated functional decline restrict the ability to consi...

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Detalles Bibliográficos
Autores principales: McGrath, Madison, Tam, Edmund, Sladkova, Martina, AlManaie, Athbah, Zimmer, Matthew, de Peppo, Giuseppe Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329105/
https://www.ncbi.nlm.nih.gov/pubmed/30635059
http://dx.doi.org/10.1186/s13287-018-1119-3