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Reduced scan range abdominopelvic CT in patients with suspected acute appendicitis - impact on diagnostic accuracy and effective radiation dose

BACKGROUND: To evaluate a reduced range CT protocol in patients with suspected acute appendicitis as compared to standard abdominal CT regarding diagnostic performance, effective radiation dose and organ doses. METHODS: In this study, we retrospectively included 90 patients (43 female, mean age 56.7...

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Autores principales: Zinsser, Dominik, Maurer, Michael, Do, Phuong-Linh, Weiß, Jakob, Notohamiprodjo, Mike, Bamberg, Fabian, Othman, Ahmed E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329115/
https://www.ncbi.nlm.nih.gov/pubmed/30635023
http://dx.doi.org/10.1186/s12880-019-0304-x
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author Zinsser, Dominik
Maurer, Michael
Do, Phuong-Linh
Weiß, Jakob
Notohamiprodjo, Mike
Bamberg, Fabian
Othman, Ahmed E.
author_facet Zinsser, Dominik
Maurer, Michael
Do, Phuong-Linh
Weiß, Jakob
Notohamiprodjo, Mike
Bamberg, Fabian
Othman, Ahmed E.
author_sort Zinsser, Dominik
collection PubMed
description BACKGROUND: To evaluate a reduced range CT protocol in patients with suspected acute appendicitis as compared to standard abdominal CT regarding diagnostic performance, effective radiation dose and organ doses. METHODS: In this study, we retrospectively included 90 patients (43 female, mean age 56.7 ± 17 years) with suspected acute appendicitis who underwent CT of abdomen and pelvis. From those CTs, we reconstructed images with a reduced scan range from L1 to the the pubic symphysis. Full range and reduced range datasets were assessed by two radiologists for i) coverage of the Appendix, ii) presence/absence of appendicitis and iii) presence of differential diagnoses. Furthermore, effective radiation doses as well as organ doses were calculated using a commercially available dose management platform (Radimetrics, Bayer HealthCare). RESULTS: The Appendix was covered by the reduced range CT in all cases. In 66 patients CT confirmed the presence of appendicitis. In 14 patients, other relevant differential diagnoses were identified by CT, whereas in 10 patients no relevant findings were detected. Both readers identified all patients with appendicitis on both full and reduced range CT. For reduced range CT, total effective dose was 39% lower than for full range CT (reduced range: 4.5 [1.9–11.2] vs. full range: 7.4 [3.3–18.8] mSv; p ≤ 0.001). Notably, a remarkable reduction of organ dose in the female breasts by 97% (0.1 [0.1–0.6] vs. 3.8 [0.5–18.8] mSv; p ≤ 0.001) and in the testicles in males by 81% (3.4 [0.7–32.7] vs. 17.6 [5.4–52.9] mSv; p ≤ 0.001) was observed for reduced range CT compared to full range CT. CONCLUSIONS: In patients with suspected acute appendicitis, reduced range abdominopelvic CT results in a comparable diagnostic performance with a remarkable reduction of total effective radiation dose and organ doses (especially breast dose in female and testicle dose in male patients) as compared to full range CT.
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spelling pubmed-63291152019-01-16 Reduced scan range abdominopelvic CT in patients with suspected acute appendicitis - impact on diagnostic accuracy and effective radiation dose Zinsser, Dominik Maurer, Michael Do, Phuong-Linh Weiß, Jakob Notohamiprodjo, Mike Bamberg, Fabian Othman, Ahmed E. BMC Med Imaging Research Article BACKGROUND: To evaluate a reduced range CT protocol in patients with suspected acute appendicitis as compared to standard abdominal CT regarding diagnostic performance, effective radiation dose and organ doses. METHODS: In this study, we retrospectively included 90 patients (43 female, mean age 56.7 ± 17 years) with suspected acute appendicitis who underwent CT of abdomen and pelvis. From those CTs, we reconstructed images with a reduced scan range from L1 to the the pubic symphysis. Full range and reduced range datasets were assessed by two radiologists for i) coverage of the Appendix, ii) presence/absence of appendicitis and iii) presence of differential diagnoses. Furthermore, effective radiation doses as well as organ doses were calculated using a commercially available dose management platform (Radimetrics, Bayer HealthCare). RESULTS: The Appendix was covered by the reduced range CT in all cases. In 66 patients CT confirmed the presence of appendicitis. In 14 patients, other relevant differential diagnoses were identified by CT, whereas in 10 patients no relevant findings were detected. Both readers identified all patients with appendicitis on both full and reduced range CT. For reduced range CT, total effective dose was 39% lower than for full range CT (reduced range: 4.5 [1.9–11.2] vs. full range: 7.4 [3.3–18.8] mSv; p ≤ 0.001). Notably, a remarkable reduction of organ dose in the female breasts by 97% (0.1 [0.1–0.6] vs. 3.8 [0.5–18.8] mSv; p ≤ 0.001) and in the testicles in males by 81% (3.4 [0.7–32.7] vs. 17.6 [5.4–52.9] mSv; p ≤ 0.001) was observed for reduced range CT compared to full range CT. CONCLUSIONS: In patients with suspected acute appendicitis, reduced range abdominopelvic CT results in a comparable diagnostic performance with a remarkable reduction of total effective radiation dose and organ doses (especially breast dose in female and testicle dose in male patients) as compared to full range CT. BioMed Central 2019-01-11 /pmc/articles/PMC6329115/ /pubmed/30635023 http://dx.doi.org/10.1186/s12880-019-0304-x Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Zinsser, Dominik
Maurer, Michael
Do, Phuong-Linh
Weiß, Jakob
Notohamiprodjo, Mike
Bamberg, Fabian
Othman, Ahmed E.
Reduced scan range abdominopelvic CT in patients with suspected acute appendicitis - impact on diagnostic accuracy and effective radiation dose
title Reduced scan range abdominopelvic CT in patients with suspected acute appendicitis - impact on diagnostic accuracy and effective radiation dose
title_full Reduced scan range abdominopelvic CT in patients with suspected acute appendicitis - impact on diagnostic accuracy and effective radiation dose
title_fullStr Reduced scan range abdominopelvic CT in patients with suspected acute appendicitis - impact on diagnostic accuracy and effective radiation dose
title_full_unstemmed Reduced scan range abdominopelvic CT in patients with suspected acute appendicitis - impact on diagnostic accuracy and effective radiation dose
title_short Reduced scan range abdominopelvic CT in patients with suspected acute appendicitis - impact on diagnostic accuracy and effective radiation dose
title_sort reduced scan range abdominopelvic ct in patients with suspected acute appendicitis - impact on diagnostic accuracy and effective radiation dose
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329115/
https://www.ncbi.nlm.nih.gov/pubmed/30635023
http://dx.doi.org/10.1186/s12880-019-0304-x
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