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Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid

BACKGROUND: Exosomes are a subset of extracellular vesicles 30–200 nm in diameter secreted from cells, which contain functional mRNAs and microRNAs. Cerebrospinal fluid (CSF) is the primary source for liquid biopsy to examine diseases in central nervous system. To date, there is no available method...

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Detalles Bibliográficos
Autores principales:	Otake, Kentaro, Kamiguchi, Hidenori, Hirozane, Yoshihiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Technical Advance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329125/ https://www.ncbi.nlm.nih.gov/pubmed/30630471 http://dx.doi.org/10.1186/s12920-019-0473-z

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