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Exosomes secreted by endothelial progenitor cells accelerate bone regeneration during distraction osteogenesis by stimulating angiogenesis

BACKGROUND: Distraction osteogenesis (DO) is an effective but lengthy procedure to fully induce bone regeneration in large bone defects. Accumulating evidence supports the role of exosomes secreted by endothelial progenitor cells (EPC-Exos) in stimulating angiogenesis, which is closely coupled with...

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Detalles Bibliográficos
Autores principales: Jia, Yachao, Zhu, Yu, Qiu, Shuo, Xu, Jia, Chai, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329174/
https://www.ncbi.nlm.nih.gov/pubmed/30635031
http://dx.doi.org/10.1186/s13287-018-1115-7