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Risk scores for predicting dysphagia in critically ill patients after cardiac surgery

BACKGROUND: This study aimed at developing and validating a scoring model to stratify critically ill patients after cardiac surgery based on risk for dysphagia, a common but often neglected complication. METHODS: Data were prospectively collected and analyzed from January 2016 to June 2017 from 395...

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Autores principales: Zhou, Xiao-Dong, Dong, Wei-Hua, Zhao, Chu-Huan, Feng, Xia-Fei, Wen, Wei-Wei, Tu, Wen-Yi, Cai, Meng-Xing, Xu, Tian-Cheng, Xie, Qiang-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329180/
https://www.ncbi.nlm.nih.gov/pubmed/30630421
http://dx.doi.org/10.1186/s12871-019-0680-3
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author Zhou, Xiao-Dong
Dong, Wei-Hua
Zhao, Chu-Huan
Feng, Xia-Fei
Wen, Wei-Wei
Tu, Wen-Yi
Cai, Meng-Xing
Xu, Tian-Cheng
Xie, Qiang-Li
author_facet Zhou, Xiao-Dong
Dong, Wei-Hua
Zhao, Chu-Huan
Feng, Xia-Fei
Wen, Wei-Wei
Tu, Wen-Yi
Cai, Meng-Xing
Xu, Tian-Cheng
Xie, Qiang-Li
author_sort Zhou, Xiao-Dong
collection PubMed
description BACKGROUND: This study aimed at developing and validating a scoring model to stratify critically ill patients after cardiac surgery based on risk for dysphagia, a common but often neglected complication. METHODS: Data were prospectively collected and analyzed from January 2016 to June 2017 from 395 consecutive post cardiac surgery patients at the cardiac care unit (CCU) at a single center; 103 (26.1%) developed dysphagia. Univariate and multivariate logistic analyses were used to identify independent predictors for dysphagia. The survival nomogram was developed on the basis of a multivariable Cox model, which allowed us to obtain survival probability estimations. The predictive performance of the nomogram was verified for discrimination and calibration. Areas under receiver operating characteristic curve analysis were used to illustrate and evaluate the diagnostic performance of the novel model. RESULTS: The final novel scoring model, named SSG-OD, consists of three independent factors: gastric intubation (OR = 1.024, 95% CI 1.015–1.033), sedative drug use duration (OR = 1.031, 95% CI 1.001–1.063) and stroke or not (OR = 6.182, 95% CI 3.028–12.617). SSG-OD identified patients at risk for dysphagia with sensitivity of 68.5% and specificity of 89.0% (OR = 0.833, 95% CI: 0.782–0.884). The positive and negative likelihood ratios were 6.22 and 0.35. CONCLUSIONS: The novel SSG-OD scoring system to risk stratify CCU patients for dysphagia is an easy-to-use bedside prognostication aid with good predictive performance and the potential to reduce aspiration incidence and accelerate recovery.
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spelling pubmed-63291802019-01-16 Risk scores for predicting dysphagia in critically ill patients after cardiac surgery Zhou, Xiao-Dong Dong, Wei-Hua Zhao, Chu-Huan Feng, Xia-Fei Wen, Wei-Wei Tu, Wen-Yi Cai, Meng-Xing Xu, Tian-Cheng Xie, Qiang-Li BMC Anesthesiol Research Article BACKGROUND: This study aimed at developing and validating a scoring model to stratify critically ill patients after cardiac surgery based on risk for dysphagia, a common but often neglected complication. METHODS: Data were prospectively collected and analyzed from January 2016 to June 2017 from 395 consecutive post cardiac surgery patients at the cardiac care unit (CCU) at a single center; 103 (26.1%) developed dysphagia. Univariate and multivariate logistic analyses were used to identify independent predictors for dysphagia. The survival nomogram was developed on the basis of a multivariable Cox model, which allowed us to obtain survival probability estimations. The predictive performance of the nomogram was verified for discrimination and calibration. Areas under receiver operating characteristic curve analysis were used to illustrate and evaluate the diagnostic performance of the novel model. RESULTS: The final novel scoring model, named SSG-OD, consists of three independent factors: gastric intubation (OR = 1.024, 95% CI 1.015–1.033), sedative drug use duration (OR = 1.031, 95% CI 1.001–1.063) and stroke or not (OR = 6.182, 95% CI 3.028–12.617). SSG-OD identified patients at risk for dysphagia with sensitivity of 68.5% and specificity of 89.0% (OR = 0.833, 95% CI: 0.782–0.884). The positive and negative likelihood ratios were 6.22 and 0.35. CONCLUSIONS: The novel SSG-OD scoring system to risk stratify CCU patients for dysphagia is an easy-to-use bedside prognostication aid with good predictive performance and the potential to reduce aspiration incidence and accelerate recovery. BioMed Central 2019-01-10 /pmc/articles/PMC6329180/ /pubmed/30630421 http://dx.doi.org/10.1186/s12871-019-0680-3 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Zhou, Xiao-Dong
Dong, Wei-Hua
Zhao, Chu-Huan
Feng, Xia-Fei
Wen, Wei-Wei
Tu, Wen-Yi
Cai, Meng-Xing
Xu, Tian-Cheng
Xie, Qiang-Li
Risk scores for predicting dysphagia in critically ill patients after cardiac surgery
title Risk scores for predicting dysphagia in critically ill patients after cardiac surgery
title_full Risk scores for predicting dysphagia in critically ill patients after cardiac surgery
title_fullStr Risk scores for predicting dysphagia in critically ill patients after cardiac surgery
title_full_unstemmed Risk scores for predicting dysphagia in critically ill patients after cardiac surgery
title_short Risk scores for predicting dysphagia in critically ill patients after cardiac surgery
title_sort risk scores for predicting dysphagia in critically ill patients after cardiac surgery
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329180/
https://www.ncbi.nlm.nih.gov/pubmed/30630421
http://dx.doi.org/10.1186/s12871-019-0680-3
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