The ESCRT and autophagy machineries cooperate to repair ESX-1-dependent damage at the Mycobacterium-containing vacuole but have opposite impact on containing the infection

Phagocytic cells capture and kill most invader microbes within the bactericidal phagosome, but some pathogens subvert killing by damaging the compartment and escaping to the cytosol. To prevent the leakage of pathogen virulence and host defence factors, as well as bacteria escape, host cells have to...

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Detalles Bibliográficos
Autores principales: López-Jiménez, Ana T., Cardenal-Muñoz, Elena, Leuba, Florence, Gerstenmaier, Lilli, Barisch, Caroline, Hagedorn, Monica, King, Jason S., Soldati, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329560/
https://www.ncbi.nlm.nih.gov/pubmed/30596802
http://dx.doi.org/10.1371/journal.ppat.1007501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329560/
https://www.ncbi.nlm.nih.gov/pubmed/30596802
http://dx.doi.org/10.1371/journal.ppat.1007501

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