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The flow responsive transcription factor Klf2 is required for myocardial wall integrity by modulating Fgf signaling
Complex interplay between cardiac tissues is crucial for their integrity. The flow responsive transcription factor KLF2, which is expressed in the endocardium, is vital for cardiovascular development but its exact role remains to be defined. To this end, we mutated both klf2 paralogues in zebrafish,...
Autores principales: | Rasouli, Seyed Javad, El-Brolosy, Mohamed, Tsedeke, Ayele Taddese, Bensimon-Brito, Anabela, Ghanbari, Parisa, Maischein, Hans-Martin, Kuenne, Carsten, Stainier, Didier Y |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329608/ https://www.ncbi.nlm.nih.gov/pubmed/30592462 http://dx.doi.org/10.7554/eLife.38889 |
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