Magnusiomyces clavatus infection in a child after allogeneic hematotopoetic stem cell transplantation: Diagnostic and therapeutic implications

Magnusiomyces clavatus is an ascomycetous fungus causing invasive disease in immuno-compromised patients. Neutropenia, contaminated venous catheters, previous antifungal treatment are risk factors for this infection. We report a case of Magnusiomyces clavatus fungemia with pulmonary, renal and skin...

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Autores principales: Leoni, Massimiliano, Riccardi, Niccolò, Rotulo, Gioacchino Andrea, Godano, Elisabetta, Faraci, Maura, Bandettini, Roberto, Esposto, Maria Carmela, Castagnola, Elio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329693/
https://www.ncbi.nlm.nih.gov/pubmed/30656133
http://dx.doi.org/10.1016/j.mmcr.2018.12.005
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author Leoni, Massimiliano
Riccardi, Niccolò
Rotulo, Gioacchino Andrea
Godano, Elisabetta
Faraci, Maura
Bandettini, Roberto
Esposto, Maria Carmela
Castagnola, Elio
author_facet Leoni, Massimiliano
Riccardi, Niccolò
Rotulo, Gioacchino Andrea
Godano, Elisabetta
Faraci, Maura
Bandettini, Roberto
Esposto, Maria Carmela
Castagnola, Elio
author_sort Leoni, Massimiliano
collection PubMed
description Magnusiomyces clavatus is an ascomycetous fungus causing invasive disease in immuno-compromised patients. Neutropenia, contaminated venous catheters, previous antifungal treatment are risk factors for this infection. We report a case of Magnusiomyces clavatus fungemia with pulmonary, renal and skin localizations in a 6-year-old boy with prolonged neutropenia because of three allogeneic hematopoietic stem cell transplantations. The infection was controlled by aggressive and strictly monitored combination therapy with voriconazole and liposomial-ampthotericine-B along with durable recover from neutropenia.
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spelling pubmed-63296932019-01-17 Magnusiomyces clavatus infection in a child after allogeneic hematotopoetic stem cell transplantation: Diagnostic and therapeutic implications Leoni, Massimiliano Riccardi, Niccolò Rotulo, Gioacchino Andrea Godano, Elisabetta Faraci, Maura Bandettini, Roberto Esposto, Maria Carmela Castagnola, Elio Med Mycol Case Rep Case Report Magnusiomyces clavatus is an ascomycetous fungus causing invasive disease in immuno-compromised patients. Neutropenia, contaminated venous catheters, previous antifungal treatment are risk factors for this infection. We report a case of Magnusiomyces clavatus fungemia with pulmonary, renal and skin localizations in a 6-year-old boy with prolonged neutropenia because of three allogeneic hematopoietic stem cell transplantations. The infection was controlled by aggressive and strictly monitored combination therapy with voriconazole and liposomial-ampthotericine-B along with durable recover from neutropenia. Elsevier 2018-12-21 /pmc/articles/PMC6329693/ /pubmed/30656133 http://dx.doi.org/10.1016/j.mmcr.2018.12.005 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Leoni, Massimiliano
Riccardi, Niccolò
Rotulo, Gioacchino Andrea
Godano, Elisabetta
Faraci, Maura
Bandettini, Roberto
Esposto, Maria Carmela
Castagnola, Elio
Magnusiomyces clavatus infection in a child after allogeneic hematotopoetic stem cell transplantation: Diagnostic and therapeutic implications
title Magnusiomyces clavatus infection in a child after allogeneic hematotopoetic stem cell transplantation: Diagnostic and therapeutic implications
title_full Magnusiomyces clavatus infection in a child after allogeneic hematotopoetic stem cell transplantation: Diagnostic and therapeutic implications
title_fullStr Magnusiomyces clavatus infection in a child after allogeneic hematotopoetic stem cell transplantation: Diagnostic and therapeutic implications
title_full_unstemmed Magnusiomyces clavatus infection in a child after allogeneic hematotopoetic stem cell transplantation: Diagnostic and therapeutic implications
title_short Magnusiomyces clavatus infection in a child after allogeneic hematotopoetic stem cell transplantation: Diagnostic and therapeutic implications
title_sort magnusiomyces clavatus infection in a child after allogeneic hematotopoetic stem cell transplantation: diagnostic and therapeutic implications
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329693/
https://www.ncbi.nlm.nih.gov/pubmed/30656133
http://dx.doi.org/10.1016/j.mmcr.2018.12.005
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