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Recombinant AAV-CEA Tumor Vaccine in Combination with an Immune Adjuvant Breaks Tolerance and Provides Protective Immunity
Carcinoembryonic antigen (CEA) is a human glycoprotein involved in cellular adhesion and expressed during human fetal development. Although expression of CEA largely ceases prior to birth, several human epithelial cancers, including colorectal, gastric, squamous esophageal, and breast carcinomas hav...
Autores principales: | Hensel, Jonathan A., Khattar, Vinayak, Ashton, Reading, Ponnazhagan, Selvarangan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329706/ https://www.ncbi.nlm.nih.gov/pubmed/30666318 http://dx.doi.org/10.1016/j.omto.2018.12.004 |
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