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Fibroblast polarization over the myocardial infarction time continuum shifts roles from inflammation to angiogenesis

Cardiac fibroblasts are the major producers of extracellular matrix (ECM) to form infarct scar. We hypothesized that fibroblasts undergo a spectrum of phenotype states over the course of myocardial infarction (MI) from early onset to scar formation. Fibroblasts were isolated from the infarct region...

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Detalles Bibliográficos
Autores principales: Mouton, Alan J., Ma, Yonggang, Rivera Gonzalez, Osvaldo J., Daseke, Michael J., Flynn, Elizabeth R., Freeman, Tom C., Garrett, Michael R., DeLeon-Pennell, Kristine Y., Lindsey, Merry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329742/
https://www.ncbi.nlm.nih.gov/pubmed/30635789
http://dx.doi.org/10.1007/s00395-019-0715-4