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Fibroblast polarization over the myocardial infarction time continuum shifts roles from inflammation to angiogenesis
Cardiac fibroblasts are the major producers of extracellular matrix (ECM) to form infarct scar. We hypothesized that fibroblasts undergo a spectrum of phenotype states over the course of myocardial infarction (MI) from early onset to scar formation. Fibroblasts were isolated from the infarct region...
Autores principales: | Mouton, Alan J., Ma, Yonggang, Rivera Gonzalez, Osvaldo J., Daseke, Michael J., Flynn, Elizabeth R., Freeman, Tom C., Garrett, Michael R., DeLeon-Pennell, Kristine Y., Lindsey, Merry L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329742/ https://www.ncbi.nlm.nih.gov/pubmed/30635789 http://dx.doi.org/10.1007/s00395-019-0715-4 |
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