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Computational insights into the role of α-strand/sheet in aggregation of α-synuclein

The α-synuclein is a major component of amyloid fibrils found in Lewy bodies, the characteristic intracellular proteinaceous deposits which are pathological hallmarks of neurodegenerative diseases such as Parkinson’s disease (PD) and dementia. It is an intrinsically disordered protein that may under...

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Detalles Bibliográficos
Autores principales:	Balupuri, Anand, Choi, Kwang-Eun, Kang, Nam Sook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329781/ https://www.ncbi.nlm.nih.gov/pubmed/30635607 http://dx.doi.org/10.1038/s41598-018-37276-1

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