Dispersible hydrogel force sensors reveal patterns of solid mechanical stress in multicellular spheroid cultures

Understanding how forces orchestrate tissue formation requires technologies to map internal tissue stress at cellular length scales. Here, we develop ultrasoft mechanosensors that visibly deform under less than 10 Pascals of cell-generated stress. By incorporating these mechanosensors into multicell...

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Detalles Bibliográficos
Autores principales: Lee, Wontae, Kalashnikov, Nikita, Mok, Stephanie, Halaoui, Ruba, Kuzmin, Elena, Putnam, Andrew J., Takayama, Shuichi, Park, Morag, McCaffrey, Luke, Zhao, Ruogang, Leask, Richard L., Moraes, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329783/
https://www.ncbi.nlm.nih.gov/pubmed/30635553
http://dx.doi.org/10.1038/s41467-018-07967-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329783/
https://www.ncbi.nlm.nih.gov/pubmed/30635553
http://dx.doi.org/10.1038/s41467-018-07967-4

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