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Dispersible hydrogel force sensors reveal patterns of solid mechanical stress in multicellular spheroid cultures
Understanding how forces orchestrate tissue formation requires technologies to map internal tissue stress at cellular length scales. Here, we develop ultrasoft mechanosensors that visibly deform under less than 10 Pascals of cell-generated stress. By incorporating these mechanosensors into multicell...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329783/ https://www.ncbi.nlm.nih.gov/pubmed/30635553 http://dx.doi.org/10.1038/s41467-018-07967-4 |