Cargando…

Prognostic Value of PDZ-Binding Kinase/T-LAK Cell-Originated Protein Kinase (PBK/TOPK) in Patients with Cancer

Background: PDZ-binding kinase/T-LAK cell-originated protein kinase (PBK/TOPK) plays a critical role in tumorigenesis and cancer progression. However, the prognostic roles in cancer patients are inconsistent or even controversial. Therefore, we performed a meta-analysis to investigate the prognostic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yi, Yang, Xianjin, Wang, Rong, Zhang, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329853/ https://www.ncbi.nlm.nih.gov/pubmed/30662533 http://dx.doi.org/10.7150/jca.28216

Ejemplares similares

T‐LAK cell‐originated protein kinase (TOPK) is a Novel Prognostic and Therapeutic Target in Chordoma
por: Thanindratarn, Pichaya, et al.
Publicado: (2020)

T‐LAK cell‐originated protein kinase (TOPK): an emerging prognostic biomarker and therapeutic target in osteosarcoma
por: Thanindratarn, Pichaya, et al.
Publicado: (2021)

T-LAK cell-originated protein kinase (TOPK): an emerging target for cancer-specific therapeutics
por: Herbert, Katharine J., et al.
Publicado: (2018)

Baicalin suppresses lung cancer growth by targeting PDZ-binding kinase/T-LAK cell-originated protein kinase
por: Diao, Xin, et al.
Publicado: (2019)

TOPK (T‐LAK cell‐originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer
por: Park, Jae‐Hyun, et al.
Publicado: (2017)

PDZ Binding Kinase/T-LAK Cell-Derived Protein Kinase Plays an Oncogenic Role and Promotes Immune Escape in Human Tumors
por: Feng, Tingting, et al.
Publicado: (2021)

PBK/TOPK Inhibitor Suppresses the Progression of Prolactinomas
por: Zhu, Kejing, et al.
Publicado: (2022)

Ginsenoside Rh2 inhibiting HCT116 colon cancer cell proliferation through blocking PDZ-binding kinase/T-LAK cell-originated protein kinase
por: Yang, Jianjun, et al.
Publicado: (2016)

MicroRNA-216b-3p inhibits lung adenocarcinoma cell growth via regulating PDZ binding kinase/T-LAK-cell-originated protein kinase
por: Chai, Yaqin, et al.
Publicado: (2018)

PBK/TOPK Expression Predicts Prognosis in Oral Cancer
por: Chang, Chin-Fang, et al.
Publicado: (2016)

PBK/TOPK: A Therapeutic Target Worthy of Attention
por: Han, Ziping, et al.
Publicado: (2021)

PBK/TOPK: An Effective Drug Target with Diverse Therapeutic Potential
por: Huang, Hai, et al.
Publicado: (2021)

PBK/TOPK Is a Favorable Prognostic Biomarker Correlated with Antitumor Immunity in Colon Cancers
por: Lee, Dong-Hee, et al.
Publicado: (2022)

Identification of the oncogenic kinase TOPK/PBK as a master mitotic regulator of C2H2 zinc finger proteins
por: Rizkallah, Raed, et al.
Publicado: (2015)

PBK/TOPK mediates geranylgeranylation signaling for breast cancer cell proliferation
por: Dou, Xiaoyan, et al.
Publicado: (2015)

PDZ-binding kinase/T-LAK cell-originated protein kinase is a target of the fucoidan from brown alga Fucus evanescens in the prevention of EGF-induced neoplastic cell transformation and colon cancer growth
por: Vishchuk, Olesia S., et al.
Publicado: (2016)

Corrigendum: Eupafolin Suppresses Esophagus Cancer Growth by Targeting T-LAK Cell-Originated Protein Kinase Protein Kinase
por: Fan, Xiaoming, et al.
Publicado: (2020)

PBK/TOPK overexpression and survival in solid tumors: A PRISMA-compliant meta-analysis
por: Xu, Ming, et al.
Publicado: (2019)

Eupafolin Suppresses Esophagus Cancer Growth by Targeting T-LAK Cell-Originated Protein Kinase
por: Fan, Xiaoming, et al.
Publicado: (2019)

Overexpression of PBK/TOPK relates to poor prognosis of patients with breast cancer: a retrospective analysis
por: Qiao, Liang, et al.
Publicado: (2022)

Overexpression of PBK/TOPK relates to tumour malignant potential and poor outcome of gastric carcinoma
por: Ohashi, Takuma, et al.
Publicado: (2017)

The T-LAK Cell-originated Protein Kinase Signal Pathway Promotes Colorectal Cancer Metastasis
por: Zykova, Tatyana A., et al.
Publicado: (2017)

PDZ binding kinase (PBK) is a theranostic target for nasopharyngeal carcinoma: driving tumor growth via ROS signaling and correlating with patient survival
por: Wang, Meng-Yao, et al.
Publicado: (2016)

Glycycoumarin exerts anti-liver cancer activity by directly targeting T-LAK cell-originated protein kinase
por: Song, Xinhua, et al.
Publicado: (2016)

TOPK/PBK is phosphorylated by ERK2 at serine 32, promotes tumorigenesis and is involved in sorafenib resistance in RCC
por: Sun, Huimin, et al.
Publicado: (2022)

T-lymphokine-activated killer cell-originated protein kinase (TOPK) as a prognostic factor and a potential therapeutic target in glioma
por: Quan, Chuntao, et al.
Publicado: (2017)

Paeonol suppresses solar ultraviolet-induced skin inflammation by targeting T-LAK cell-originated protein kinase
por: Xue, Peipei, et al.
Publicado: (2017)

Targeting PBK/TOPK decreases growth and survival of glioma initiating cells in vitro and attenuates tumor growth in vivo
por: Joel, Mrinal, et al.
Publicado: (2015)

Cefradine blocks solar-ultraviolet induced skin inflammation through direct inhibition of T-LAK cell-originated protein kinase
por: Fan, Xiaoming, et al.
Publicado: (2016)

PBK/TOPK inhibitor OTS964 resistance is mediated by ABCB1-dependent transport function in cancer: in vitro and in vivo study
por: Yang, Yuqi, et al.
Publicado: (2022)

PBK/TOPK enhances aggressive phenotype in prostate cancer via β-catenin-TCF/LEF-mediated matrix metalloproteinases production and invasion
por: Brown-Clay, Joshua D., et al.
Publicado: (2015)

T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia
por: Alachkar, Houda, et al.
Publicado: (2015)

Erratum: PBK/TOPK enhances aggressive phenotype in prostate cancer via β-catenin-TCF/LEF-mediated matrix metalloproteinases production and invasion
por: Brown-Clay, Joshua D., et al.
Publicado: (2016)

Targeting the T-Lak cell originated protein kinase by OTS964 shrinks the size of power-law coded heterogeneous glioma stem cell populations
por: Sugimori, Michiya, et al.
Publicado: (2017)

The Protective Role of the TOPK/PBK Pathway in Myocardial Ischemia/Reperfusion and H(2)O(2)-Induced Injury in H9C2 Cardiomyocytes
por: Sun, Guozhe, et al.
Publicado: (2016)

Cytoplasmic, nuclear, and total PBK/TOPK expression is associated with prognosis in colorectal cancer patients: A retrospective analysis based on immunohistochemistry stain of tissue microarrays
por: Su, Tzu-Cheng, et al.
Publicado: (2018)

LIN28B promotes neuroblastoma metastasis and regulates PDZ binding kinase
por: Chen, Dongdong, et al.
Publicado: (2020)

TOPK promotes lung cancer resistance to EGFR tyrosine kinase inhibitors by phosphorylating and activating c-Jun
por: Li, Ying, et al.
Publicado: (2016)

High expression of PDZ-binding kinase is correlated with poor prognosis and immune infiltrates in hepatocellular carcinoma
por: Mu, Wei, et al.
Publicado: (2022)

PDZ-Binding Kinase-Dependent Transcriptional Regulation of CCNB2 Promotes Tumorigenesis and Radio-Resistance in Glioblastoma
por: Mao, Ping, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_m3t4puuojnhva87ntg92ksgpmn