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In-hospital outcome of patients with post-MI VSD: a single-center study
INTRODUCTION: Ventricular septal defect (VSD) is a rare but life-threatening complication of acute myocardial infarction (AMI). There is a paucity of data regarding the natural history of this devastating complication of myocardial infarction in the Middle East region with restricted financial resou...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329881/ https://www.ncbi.nlm.nih.gov/pubmed/30647745 http://dx.doi.org/10.5114/kitp.2018.80918 |
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author | Abbasnejad, Mohsen vand, Mehdi Tahmasebi Khamnian, Zhila Separham, Ahmad |
author_facet | Abbasnejad, Mohsen vand, Mehdi Tahmasebi Khamnian, Zhila Separham, Ahmad |
author_sort | Abbasnejad, Mohsen |
collection | PubMed |
description | INTRODUCTION: Ventricular septal defect (VSD) is a rare but life-threatening complication of acute myocardial infarction (AMI). There is a paucity of data regarding the natural history of this devastating complication of myocardial infarction in the Middle East region with restricted financial resources and unsolved major health problems. AIM: To evaluate the clinical presentation and in-hospital outcome of patients with post-infarction VSD over a 10-year period in a tertiary center in northwest Iran. MATERIAL AND METHODS: Data from 64 consecutive patients with VSD complicating AMI were retrospectively analyzed from March 2005 to May 2015. RESULTS: The mean age of the patients was 71.62 ±9.38 years with 57.8% of them being female. The VSDs were anterior in 52 (82%) patients. More than half of patients were in cardiogenic shock during the initial presentation. Multivessel coronary artery disease was found on coronary angiography in 70.3% of patients. In-hospital mortality was 82.8%. Multivariate analysis revealed cardiogenic shock (HR = 12.5, p = 0.001) as the only independent predictor of in-hospital mortality and surgical treatment as the only predictor of in-hospital survival (HR = 0.2, p = 0.02). CONCLUSIONS: Our study demonstrated that VSD complicating myocardial infarction had an extremely high in-hospital mortality rate. Cardiogenic shock was the only independent predictor of in-hospital mortality and surgical treatment was the only predictor of in-hospital survival. |
format | Online Article Text |
id | pubmed-6329881 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Termedia Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-63298812019-01-15 In-hospital outcome of patients with post-MI VSD: a single-center study Abbasnejad, Mohsen vand, Mehdi Tahmasebi Khamnian, Zhila Separham, Ahmad Kardiochir Torakochirurgia Pol Original Paper INTRODUCTION: Ventricular septal defect (VSD) is a rare but life-threatening complication of acute myocardial infarction (AMI). There is a paucity of data regarding the natural history of this devastating complication of myocardial infarction in the Middle East region with restricted financial resources and unsolved major health problems. AIM: To evaluate the clinical presentation and in-hospital outcome of patients with post-infarction VSD over a 10-year period in a tertiary center in northwest Iran. MATERIAL AND METHODS: Data from 64 consecutive patients with VSD complicating AMI were retrospectively analyzed from March 2005 to May 2015. RESULTS: The mean age of the patients was 71.62 ±9.38 years with 57.8% of them being female. The VSDs were anterior in 52 (82%) patients. More than half of patients were in cardiogenic shock during the initial presentation. Multivessel coronary artery disease was found on coronary angiography in 70.3% of patients. In-hospital mortality was 82.8%. Multivariate analysis revealed cardiogenic shock (HR = 12.5, p = 0.001) as the only independent predictor of in-hospital mortality and surgical treatment as the only predictor of in-hospital survival (HR = 0.2, p = 0.02). CONCLUSIONS: Our study demonstrated that VSD complicating myocardial infarction had an extremely high in-hospital mortality rate. Cardiogenic shock was the only independent predictor of in-hospital mortality and surgical treatment was the only predictor of in-hospital survival. Termedia Publishing House 2018-12-31 2018-12 /pmc/articles/PMC6329881/ /pubmed/30647745 http://dx.doi.org/10.5114/kitp.2018.80918 Text en Copyright: © 2018 Polish Society of Cardiothoracic Surgeons (Polskie Towarzystwo KardioTorakochirurgów) and the editors of the Polish Journal of Cardio-Thoracic Surgery (Kardiochirurgia i Torakochirurgia Polska) http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license. |
spellingShingle | Original Paper Abbasnejad, Mohsen vand, Mehdi Tahmasebi Khamnian, Zhila Separham, Ahmad In-hospital outcome of patients with post-MI VSD: a single-center study |
title | In-hospital outcome of patients with post-MI VSD: a single-center study |
title_full | In-hospital outcome of patients with post-MI VSD: a single-center study |
title_fullStr | In-hospital outcome of patients with post-MI VSD: a single-center study |
title_full_unstemmed | In-hospital outcome of patients with post-MI VSD: a single-center study |
title_short | In-hospital outcome of patients with post-MI VSD: a single-center study |
title_sort | in-hospital outcome of patients with post-mi vsd: a single-center study |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329881/ https://www.ncbi.nlm.nih.gov/pubmed/30647745 http://dx.doi.org/10.5114/kitp.2018.80918 |
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