Cargando…

GALNT6 Promotes Tumorigenicity and Metastasis of Breast Cancer Cell via β-catenin/MUC1-C Signaling Pathway

Polypeptide N-acetylgalactosaminyl transferase-6 (GALNT6), a member of the N-acetyl-D-galactosamine transferase family, was shown to be over-expression in mammary cancer and could be used as a biomarker. However, its roles and underlying mechanisms in the pathogenesis of breast cancer are still uncl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mao, Yingge, Zhang, Yuqi, Fan, Sairong, Chen, Lvao, Tang, Lili, Chen, Xiaoming, Lyu, Jianxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329923/ https://www.ncbi.nlm.nih.gov/pubmed/30662357 http://dx.doi.org/10.7150/ijbs.29048

Ejemplares similares

GALNT6 Promotes Tumorigenicity and Metastasis of Breast Cancer Cell via β-catenin/MUC1-C Signaling Pathway: Erratum
por: Mao, Yingge, et al.
Publicado: (2021)

Knocking down GALNT6 promotes pyroptosis of pancreatic ductal adenocarcinoma cells through NF-κB/NLRP3/GSDMD and GSDME signaling pathway
por: Ding, Mengyang, et al.
Publicado: (2023)

Effect of MUC1/β-catenin interaction on the tumorigenic capacity of pancreatic CD133(+) cells
por: Sousa, Andreia Mota, et al.
Publicado: (2016)

FUT2 promotes the tumorigenicity and metastasis of colorectal cancer cells via the Wnt/β-catenin pathway
por: Liu, Peng, et al.
Publicado: (2023)

GATA6 promotes epithelial-mesenchymal transition and metastasis through MUC1/β-catenin pathway in cholangiocarcinoma
por: Deng, Xiang, et al.
Publicado: (2020)

RUNX3-Regulated GALNT6 Promotes the Migration and Invasion of Hepatocellular Carcinoma Cells by Mediating O-Glycosylation of MUC1
por: Gao, Fei, et al.
Publicado: (2022)

Retracted: RUNX3-Regulated GALNT6 Promotes the Migration and Invasion of Hepatocellular Carcinoma Cells by Mediating O-Glycosylation of MUC1
por: Markers, Disease
Publicado: (2023)

Role of GALNT14 in lung metastasis of breast cancer
por: Kim, Mi-Young
Publicado: (2017)

SDCBP‐AS1 destabilizes β‐catenin by regulating ubiquitination and SUMOylation of hnRNP K to suppress gastric tumorigenicity and metastasis
por: Han, Jing, et al.
Publicado: (2022)

C-terminus of MUC16 activates Wnt signaling pathway through its interaction with β-catenin to promote tumorigenesis and metastasis
por: Liu, Qi, et al.
Publicado: (2016)

Tumor Suppressive Role of MUC6 in Wilms Tumor via Autophagy-Dependent β-Catenin Degradation
por: Liu, Bai-Hui, et al.
Publicado: (2022)

GALNT6 promotes breast cancer metastasis by increasing mucin-type O-glycosylation of α2M
por: Liu, Chang, et al.
Publicado: (2020)

Cell membrane-anchored MUC4 promotes tumorigenicity in epithelial carcinomas
por: Xia, Pengpeng, et al.
Publicado: (2016)

GALNT1 Enhances Malignant Phenotype of Gastric Cancer via Modulating CD44 Glycosylation to Activate the Wnt/β-catenin Signaling Pathway
por: Zhang, Junchang, et al.
Publicado: (2022)

MUC1 regulates cyclin D1 gene expression through p120 catenin and β-catenin
por: Liu, X, et al.
Publicado: (2014)

No major tumorigenic role for β-catenin in serrated as opposed to conventional colorectal adenomas
por: Yamamoto, T, et al.
Publicado: (2003)

β-Catenin Is Required for the Tumorigenic Behavior of Triple-Negative Breast Cancer Cells
por: Xu, Jinhua, et al.
Publicado: (2015)

Transcription factor AP-4 promotes tumorigenic capability and activates the Wnt/β-catenin pathway in hepatocellular carcinoma
por: Song, Junwei, et al.
Publicado: (2018)

FUT2 Facilitates Autophagy and Suppresses Apoptosis via p53 and JNK Signaling in Lung Adenocarcinoma Cells
por: Zhang, Yuqi, et al.
Publicado: (2022)

Molecular Interactions between MUC1 Epithelial Mucin, β-Catenin, and CagA Proteins
por: Guang, Wei, et al.
Publicado: (2012)

KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1
por: Liu, Wenxue, et al.
Publicado: (2021)

GALNT6 promotes invasion and metastasis of human lung adenocarcinoma cells through O-glycosylating chaperone protein GRP78
por: Song, Jing, et al.
Publicado: (2020)

Achyranthes bidentata Polysaccharide Activates Nuclear Factor-Kappa B and Promotes Cytokine Production in J774A.1 Cells Through TLR4/MyD88 Signaling Pathway
por: Fan, Sairong, et al.
Publicado: (2021)

TIMMDC1 Knockdown Inhibits Growth and Metastasis of Gastric Cancer Cells through Metabolic Inhibition and AKT/GSK3β/β-Catenin Signaling Pathway
por: Liu, Yuan, et al.
Publicado: (2018)

MiR-744 increases tumorigenicity of pancreatic cancer by activating Wnt/β-catenin pathway
por: Zhou, Wei, et al.
Publicado: (2015)

GALNT6 expression enhances aggressive phenotypes of ovarian cancer cells by regulating EGFR activity
por: Lin, Tzu-Chi, et al.
Publicado: (2017)

Human MUC4 mucin induces ultra-structural changes and tumorigenicity in pancreatic cancer cells
por: Moniaux, N, et al.
Publicado: (2007)

High Expression of N-Acetylgalactosaminyltransferase 1 (GALNT1) Associated with Invasion, Metastasis, and Proliferation in Osteosarcoma
por: Zhang, Liwen, et al.
Publicado: (2020)

The Cytoplasmic Domain of MUC1 Induces Hyperplasia in the Mammary Gland and Correlates with Nuclear Accumulation of β-Catenin
por: Li, Yuan, et al.
Publicado: (2011)

The polypeptide GALNT6 Displays Redundant Functions upon Suppression of its Closest Homolog GALNT3 in Mediating Aberrant O-Glycosylation, Associated with Ovarian Cancer Progression
por: Sheta, Razan, et al.
Publicado: (2019)

MUC1, MUC2, MUC5AC, and MUC6 in colorectal cancer: expression profiles and clinical significance
por: Betge, Johannes, et al.
Publicado: (2016)

Differential expression of CK20, β-catenin, and MUC2/5AC/6 in Lynch syndrome and familial colorectal cancer type X
por: Haraldsson, Stefan, et al.
Publicado: (2017)

LGR6 Promotes Tumor Proliferation and Metastasis through Wnt/β-Catenin Signaling in Triple-Negative Breast Cancer
por: Kong, Yanan, et al.
Publicado: (2020)

Effect of rosuvastatin on the expression of candidate gene GALNT3 in atherosclerosis
por: Liu, Yanshao, et al.
Publicado: (2018)

β-Catenin Does Not Confer Tumorigenicity When Introduced into Partially Transformed Human Mesenchymal Stem Cells
por: Piperdi, Sajida, et al.
Publicado: (2012)

Galectin-3 augments tumor initiating property and tumorigenicity of lung cancer through interaction with β-catenin
por: Chung, Ling-Yen, et al.
Publicado: (2014)

Novel HER3/MUC4 oncogenic signaling aggravates the tumorigenic phenotypes of pancreatic cancer cells
por: Lakshmanan, Imayavaramban, et al.
Publicado: (2015)

SALL4 promotes the tumorigenicity of cervical cancer cells through activation of the Wnt/β‐catenin pathway via CTNNB1
por: Chen, Mei, et al.
Publicado: (2019)

Morphological Changes, Cadherin Switching, and Growth Suppression in Pancreatic Cancer by GALNT6 Knockdown()
por: Tarhan, Yunus Emre, et al.
Publicado: (2016)

Early-Stage Loss of GALNT6 Predicts Poor Clinical Outcome in Colorectal Cancer
por: Ogawa, Makiko, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rtb4gmkbvch6gf9lqfbk0gd2qg