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Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle
Proteasomes occur in all three domains of life, and are the principal molecular machines for the regulated degradation of intracellular proteins. They play key roles in the maintenance of protein homeostasis, and control vital cellular processes. While the eukaryotic 26S proteasome is extensively ch...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329974/ https://www.ncbi.nlm.nih.gov/pubmed/30559193 http://dx.doi.org/10.1073/pnas.1817752116 |