Semaphorin signaling via MICAL3 induces symmetric cell division to expand breast cancer stem-like cells

Cancer stem-like cells (CSCs) are expanded in the CSC niche by increased frequency of symmetric cell divisions at the expense of asymmetric cell divisions. The symmetric division of CSCs is important for the malignant properties of cancer; however, underlying molecular mechanisms remain largely elus...

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Detalles Bibliográficos
Autores principales: Tominaga, Kana, Minato, Hiroshi, Murayama, Takahiko, Sasahara, Asako, Nishimura, Tatsunori, Kiyokawa, Etsuko, Kanauchi, Hajime, Shimizu, Seiichiro, Sato, Ayaka, Nishioka, Kotoe, Tsuji, Ei-ichi, Yano, Masao, Ogawa, Toshihisa, Ishii, Hideshi, Mori, Masaki, Akashi, Koichi, Okamoto, Koji, Tanabe, Masahiko, Tada, Kei-ichiro, Tojo, Arinobu, Gotoh, Noriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329980/
https://www.ncbi.nlm.nih.gov/pubmed/30587593
http://dx.doi.org/10.1073/pnas.1806851116

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