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SLIDE – a web-based tool for interactive visualization of large-scale – omics data

SUMMARY: Data visualization is often regarded as a post hoc step for verifying statistically significant results in the analysis of high-throughput datasets. This common practice leaves a large amount of raw data behind, from which more information can be extracted. However, existing solutions do no...

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Detalles Bibliográficos
Autores principales: Ghosh, Soumita, Datta, Abhik, Tan, Kaisen, Choi, Hyungwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330001/
https://www.ncbi.nlm.nih.gov/pubmed/29955804
http://dx.doi.org/10.1093/bioinformatics/bty534
Descripción
Sumario:SUMMARY: Data visualization is often regarded as a post hoc step for verifying statistically significant results in the analysis of high-throughput datasets. This common practice leaves a large amount of raw data behind, from which more information can be extracted. However, existing solutions do not provide capabilities to explore large-scale raw datasets using biologically sensible queries, nor do they allow user interaction based real-time customization of graphics. To address these drawbacks, we have designed an open-source, web-based tool called Systems-Level Interactive Data Exploration, or SLIDE to visualize large-scale -omics data interactively. SLIDE’s interface makes it easier for scientists to explore quantitative expression data in multiple resolutions in a single screen. AVAILABILITY AND IMPLEMENTATION: SLIDE is publicly available under BSD license both as an online version as well as a stand-alone version at https://github.com/soumitag/SLIDE. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.