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Flux tope analysis: studying the coordination of reaction directions in metabolic networks

MOTIVATION: Elementary flux mode (EFM) analysis allows an unbiased description of metabolic networks in terms of minimal pathways (involving a minimal set of reactions). To date, the enumeration of EFMs is impracticable in genome-scale metabolic models. In a complementary approach, we introduce the...

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Detalles Bibliográficos
Autores principales: Gerstl, Matthias P, Müller, Stefan, Regensburger, Georg, Zanghellini, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330010/
https://www.ncbi.nlm.nih.gov/pubmed/30649351
http://dx.doi.org/10.1093/bioinformatics/bty550