Efficient generation of human primordial germ cell-like cells from pluripotent stem cells in a methylcellulose-based 3D system at large scale

BACKGROUND: The mechanisms underlying human germ cell development and infertility remain largely unknown due to bioethical issues and the shortage of experimental materials. Therefore, an effective in vitro induction system of human primordial germ-like cells (hPGCLCs) from human pluripotent stem ce...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoman, Liao, Tingting, Wan, Cong, Yang, Xiaoyu, Zhao, Jiexiang, Fu, Rui, Yao, Zhaokai, Huang, Yaping, Shi, Yujia, Chang, Gang, Zheng, Yi, Luo, Fang, Liu, Zhaoting, Wang, Yu, Mao, Xinliang, Zhao, Xiao-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330037/
https://www.ncbi.nlm.nih.gov/pubmed/30643676
http://dx.doi.org/10.7717/peerj.6143

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