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Nasopharyngeal Mantle Cell Lymphoma: An Extremely Rare Entity
Mantle cell lymphoma (MCL) is a rare, aggressive subtype of non-Hodgkin lymphoma with a poor prognosis and high recurrence rate. It seldom affects the Waldeyer’s ring let alone the nasopharynx. Patients usually present at late stages of the disease leading to poor failure-free and overall survival r...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
OMJ
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330188/ https://www.ncbi.nlm.nih.gov/pubmed/30671189 http://dx.doi.org/10.5001/omj.2019.13 |
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author | Paul, Mark Asmi, Najihah Hanim Omar, Eshamsol Kamar Abdullah, Suhaila Mohamad, Irfan |
author_facet | Paul, Mark Asmi, Najihah Hanim Omar, Eshamsol Kamar Abdullah, Suhaila Mohamad, Irfan |
author_sort | Paul, Mark |
collection | PubMed |
description | Mantle cell lymphoma (MCL) is a rare, aggressive subtype of non-Hodgkin lymphoma with a poor prognosis and high recurrence rate. It seldom affects the Waldeyer’s ring let alone the nasopharynx. Patients usually present at late stages of the disease leading to poor failure-free and overall survival rates. Intensive chemotherapy regimes and autologous stem cell transplantation have reported increased survival rates. We report a relapsed case of nasopharyngeal MCL, which previously occurred in the gastrointestinal tract. The patient had undergone a hemicolectomy for colon intussusception secondary to the intraluminal lymphoma mass. He was unable to complete the treatment regime for MCL due to the adverse side effects. Oropharyngeal mass was discovered during routine outpatient follow-up, which was confirmed as nasopharyngeal MCL. We discuss the prognosis, disease progression, and possible treatments. |
format | Online Article Text |
id | pubmed-6330188 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | OMJ |
record_format | MEDLINE/PubMed |
spelling | pubmed-63301882019-01-22 Nasopharyngeal Mantle Cell Lymphoma: An Extremely Rare Entity Paul, Mark Asmi, Najihah Hanim Omar, Eshamsol Kamar Abdullah, Suhaila Mohamad, Irfan Oman Med J Case Report Mantle cell lymphoma (MCL) is a rare, aggressive subtype of non-Hodgkin lymphoma with a poor prognosis and high recurrence rate. It seldom affects the Waldeyer’s ring let alone the nasopharynx. Patients usually present at late stages of the disease leading to poor failure-free and overall survival rates. Intensive chemotherapy regimes and autologous stem cell transplantation have reported increased survival rates. We report a relapsed case of nasopharyngeal MCL, which previously occurred in the gastrointestinal tract. The patient had undergone a hemicolectomy for colon intussusception secondary to the intraluminal lymphoma mass. He was unable to complete the treatment regime for MCL due to the adverse side effects. Oropharyngeal mass was discovered during routine outpatient follow-up, which was confirmed as nasopharyngeal MCL. We discuss the prognosis, disease progression, and possible treatments. OMJ 2019-01 /pmc/articles/PMC6330188/ /pubmed/30671189 http://dx.doi.org/10.5001/omj.2019.13 Text en The OMJ is Published Bimonthly and Copyrighted 2019 by the OMSB. This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0). ( https://creativecommons.org/licenses/by-nc/4.0/). |
spellingShingle | Case Report Paul, Mark Asmi, Najihah Hanim Omar, Eshamsol Kamar Abdullah, Suhaila Mohamad, Irfan Nasopharyngeal Mantle Cell Lymphoma: An Extremely Rare Entity |
title | Nasopharyngeal Mantle Cell Lymphoma: An Extremely Rare Entity |
title_full | Nasopharyngeal Mantle Cell Lymphoma: An Extremely Rare Entity |
title_fullStr | Nasopharyngeal Mantle Cell Lymphoma: An Extremely Rare Entity |
title_full_unstemmed | Nasopharyngeal Mantle Cell Lymphoma: An Extremely Rare Entity |
title_short | Nasopharyngeal Mantle Cell Lymphoma: An Extremely Rare Entity |
title_sort | nasopharyngeal mantle cell lymphoma: an extremely rare entity |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330188/ https://www.ncbi.nlm.nih.gov/pubmed/30671189 http://dx.doi.org/10.5001/omj.2019.13 |
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