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The therapeutic potential of induced hepatocyte-like cells generated by direct reprogramming on hepatic fibrosis
BACKGROUND: Until now, there is no effective anti-fibrotic therapy available for liver cirrhosis. Stem cell therapies have been studied for the treatment of hepatic fibrosis. However, the use of embryonic stem cells or induced pluripotent stem cells (iPSC) has limitations such as ethical concern or...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330392/ https://www.ncbi.nlm.nih.gov/pubmed/30635054 http://dx.doi.org/10.1186/s13287-018-1127-3 |