In vitro synergy of sertraline and tetracycline cannot be reproduced in pigs orally challenged with a tetracycline resistant Escherichia coli

BACKGROUND: Antimicrobial helper-compounds may reverse antimicrobial resistance. Sertraline, a antidepressant drug, has been suggested as a tetracycline helper-compound. Tetracycline is the preferred antimicrobial for treatment of enteric diseases in pigs. This study is the first to evaluate the pot...

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Detalles Bibliográficos
Autores principales: Kromann, Sofie, Hvidtfeldt, Anna, Boye, Mette, Sørensen, Dorte Bratbo, Jørgensen, Steffen, Nielsen, Jens Peter, Olsen, Rikke Heidemann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330422/
https://www.ncbi.nlm.nih.gov/pubmed/30634900
http://dx.doi.org/10.1186/s12866-018-1383-5

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