Surrogacy of intermediate endpoints for overall survival in randomized controlled trials of first-line treatment for advanced soft tissue sarcoma in the pre- and post-pazopanib era: a meta-analytic evaluation

BACKGROUND: Overall survival is the true endpoint for most randomized controlled trials (RCTs) of malignant tumors, whereas progression-free survival (PFS) is considered the most reliable surrogate endpoint for overall survival (OS). The present study aimed to evaluate the correlation between surrog...

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Detalles Bibliográficos
Autores principales: Tanaka, Kazuhiro, Kawano, Masanori, Iwasaki, Tatsuya, Itonaga, Ichiro, Tsumura, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330427/
https://www.ncbi.nlm.nih.gov/pubmed/30634944
http://dx.doi.org/10.1186/s12885-019-5268-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330427/
https://www.ncbi.nlm.nih.gov/pubmed/30634944
http://dx.doi.org/10.1186/s12885-019-5268-2

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