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PENELOPE/PRIMO-calculated photon and electron spectra from clinical accelerators

BACKGROUND: The availability of photon and electron spectra in digital form from current accelerators and Monte Carlo (MC) systems is scarce, and one of the packages widely used refers to linacs with a reduced clinical use nowadays. Such spectra are mainly intended for the MC calculation of detector...

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Autores principales: Brualla, Lorenzo, Rodriguez, Miguel, Sempau, Josep, Andreo, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330451/
https://www.ncbi.nlm.nih.gov/pubmed/30634994
http://dx.doi.org/10.1186/s13014-018-1186-8
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author Brualla, Lorenzo
Rodriguez, Miguel
Sempau, Josep
Andreo, Pedro
author_facet Brualla, Lorenzo
Rodriguez, Miguel
Sempau, Josep
Andreo, Pedro
author_sort Brualla, Lorenzo
collection PubMed
description BACKGROUND: The availability of photon and electron spectra in digital form from current accelerators and Monte Carlo (MC) systems is scarce, and one of the packages widely used refers to linacs with a reduced clinical use nowadays. Such spectra are mainly intended for the MC calculation of detector-related quantities in conventional broad beams, where the use of detailed phase-space files (PSFs) is less critical than for MC-based treatment planning applications, but unlike PSFs, spectra can easily be transferred to other computer systems and users. METHODS: A set of spectra for a range of Varian linacs has been calculated using the PENELOPE/PRIMO MC system. They have been extracted from PSFs tallied for field sizes of 10 cm × 10 cm and 15 cm × 15 cm for photon and electron beams, respectively. The influence of the spectral bin width and of the beam central axis region used to extract the spectra have been analyzed. RESULTS: Spectra have been compared to those by other authors showing good agreement with those obtained using the, now superseded, EGS4/BEAM MC code, but significant differences with the most widely used photon data set. Other spectra, particularly for electron beams, have not been published previously for the machines simulated in this work. The influence of the bin width on the spectrum mean energy for 6 and 10 MV beams has been found to be negligible. The size of the region used to extract the spectra yields differences of up to 40% for the mean energies in 10 MV beams, but the maximum difference for TPR (20,10) values derived from depth-dose distributions does not exceed 2% relative to those obtained using the PSFs. This corresponds to k(Q) differences below 0.2% for a typical Farmer-type chamber, considered to be negligible for reference dosimetry. Different configurations for using electron spectra have been compared for 6 MeV beams, concluding that the geometry used for tallying the PSFs used to extract the spectra must be accounted for in subsequent calculations using the spectra as a source. CONCLUSIONS: An up-to-date set of consistent spectra for Varian accelerators suitable for the calculation of detector-related quantities in conventional broad beams has been developed and made available in digital form. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13014-018-1186-8) contains supplementary material, which is available to authorized users.
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spelling pubmed-63304512019-01-16 PENELOPE/PRIMO-calculated photon and electron spectra from clinical accelerators Brualla, Lorenzo Rodriguez, Miguel Sempau, Josep Andreo, Pedro Radiat Oncol Research BACKGROUND: The availability of photon and electron spectra in digital form from current accelerators and Monte Carlo (MC) systems is scarce, and one of the packages widely used refers to linacs with a reduced clinical use nowadays. Such spectra are mainly intended for the MC calculation of detector-related quantities in conventional broad beams, where the use of detailed phase-space files (PSFs) is less critical than for MC-based treatment planning applications, but unlike PSFs, spectra can easily be transferred to other computer systems and users. METHODS: A set of spectra for a range of Varian linacs has been calculated using the PENELOPE/PRIMO MC system. They have been extracted from PSFs tallied for field sizes of 10 cm × 10 cm and 15 cm × 15 cm for photon and electron beams, respectively. The influence of the spectral bin width and of the beam central axis region used to extract the spectra have been analyzed. RESULTS: Spectra have been compared to those by other authors showing good agreement with those obtained using the, now superseded, EGS4/BEAM MC code, but significant differences with the most widely used photon data set. Other spectra, particularly for electron beams, have not been published previously for the machines simulated in this work. The influence of the bin width on the spectrum mean energy for 6 and 10 MV beams has been found to be negligible. The size of the region used to extract the spectra yields differences of up to 40% for the mean energies in 10 MV beams, but the maximum difference for TPR (20,10) values derived from depth-dose distributions does not exceed 2% relative to those obtained using the PSFs. This corresponds to k(Q) differences below 0.2% for a typical Farmer-type chamber, considered to be negligible for reference dosimetry. Different configurations for using electron spectra have been compared for 6 MeV beams, concluding that the geometry used for tallying the PSFs used to extract the spectra must be accounted for in subsequent calculations using the spectra as a source. CONCLUSIONS: An up-to-date set of consistent spectra for Varian accelerators suitable for the calculation of detector-related quantities in conventional broad beams has been developed and made available in digital form. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13014-018-1186-8) contains supplementary material, which is available to authorized users. BioMed Central 2019-01-11 /pmc/articles/PMC6330451/ /pubmed/30634994 http://dx.doi.org/10.1186/s13014-018-1186-8 Text en © The Author(s) 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Brualla, Lorenzo
Rodriguez, Miguel
Sempau, Josep
Andreo, Pedro
PENELOPE/PRIMO-calculated photon and electron spectra from clinical accelerators
title PENELOPE/PRIMO-calculated photon and electron spectra from clinical accelerators
title_full PENELOPE/PRIMO-calculated photon and electron spectra from clinical accelerators
title_fullStr PENELOPE/PRIMO-calculated photon and electron spectra from clinical accelerators
title_full_unstemmed PENELOPE/PRIMO-calculated photon and electron spectra from clinical accelerators
title_short PENELOPE/PRIMO-calculated photon and electron spectra from clinical accelerators
title_sort penelope/primo-calculated photon and electron spectra from clinical accelerators
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330451/
https://www.ncbi.nlm.nih.gov/pubmed/30634994
http://dx.doi.org/10.1186/s13014-018-1186-8
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