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Characteristics of lipid profiles and lipid control in patients with diabetes in a tertiary hospital in Southwest China: an observational study based on electronic medical records

BACKGROUND: Diabetes is often accompanied by dyslipidemia. Lipid control is very important in the management of diabetes. There are limited real world data on the lipid control in diabetic inpatients in southwest China. METHODS: An observational study was conducted to assess the characteristics of l...

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Autores principales: Hou, Qingtao, Yu, Chuan, Li, Sheyu, Li, Yun, Zhang, Rui, Zheng, Tao, Ma, Yi, Wang, Miye, Su, Na, Wu, Ting, Liu, Zhiwen, Sheng, Xia, Li, Nan, Liu, Guanjian, Huang, Yong, Xu, Ting, Sun, Xin, Tian, Haoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330454/
https://www.ncbi.nlm.nih.gov/pubmed/30636643
http://dx.doi.org/10.1186/s12944-018-0945-8
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author Hou, Qingtao
Yu, Chuan
Li, Sheyu
Li, Yun
Zhang, Rui
Zheng, Tao
Ma, Yi
Wang, Miye
Su, Na
Wu, Ting
Liu, Zhiwen
Sheng, Xia
Li, Nan
Liu, Guanjian
Huang, Yong
Xu, Ting
Sun, Xin
Tian, Haoming
author_facet Hou, Qingtao
Yu, Chuan
Li, Sheyu
Li, Yun
Zhang, Rui
Zheng, Tao
Ma, Yi
Wang, Miye
Su, Na
Wu, Ting
Liu, Zhiwen
Sheng, Xia
Li, Nan
Liu, Guanjian
Huang, Yong
Xu, Ting
Sun, Xin
Tian, Haoming
author_sort Hou, Qingtao
collection PubMed
description BACKGROUND: Diabetes is often accompanied by dyslipidemia. Lipid control is very important in the management of diabetes. There are limited real world data on the lipid control in diabetic inpatients in southwest China. METHODS: An observational study was conducted to assess the characteristics of lipid profiles and lipid control. Diabetic patients from February 2009 to December 2013 at West China Hospital of Sichuan University were identified. RESULTS: A total of 56,784 inpatients were included and 85.9% of them had at least one lipid panel. The proportions of inpatients with optimal low-density lipoprotein cholesterol (LDL-C) level (< 2.59 mmol/L), optimal triglyceride (TG) level (< 1.70 mmol/L), optimal high-density lipoprotein cholesterol (HDL-C) level (men ≥1.04 mmol/L; women ≥1.30 mmol/L) and optimal non-high-density lipoprotein cholesterol (non-HDL-C) level (< 3.37 mmol/L) were 61.1, 64.6, 49.9 and 64.5%, respectively. Only 23.1% of inpatients obtained optimal levels for all the above four lipid parameters. Of diabetic inpatients with ischemic heart disease, the proportions of inpatients with optimal LDL-C level (< 1.81 mmol/L), optimal TG level (< 1.70 mmol/L), optimal HDL-C level (men ≥1.04 mmol/L; women ≥1.30 mmol/L) and optimal non-HDL-C level (< 2.59 mmol/L) were 38.0, 66.3, 48.1 and 48.7%, respectively. Of diabetic inpatients with cerebrovascular disease, the proportions were 28.3, 64.8, 49.9 and 38.1%, respectively. Older people and men were more likely to obtain optimal lipid levels. However, inpatients between 46 and 64 years were least likely to obtain optimal LDL-C levels. CONCLUSIONS: The lipid control of diabetic inpatients in southwest China is worrisome. Individualized strategies of lipid management should be taken to bridge the gap between the recommendations of clinical guidelines and the real situation of clinical practice. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12944-018-0945-8) contains supplementary material, which is available to authorized users.
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spelling pubmed-63304542019-01-16 Characteristics of lipid profiles and lipid control in patients with diabetes in a tertiary hospital in Southwest China: an observational study based on electronic medical records Hou, Qingtao Yu, Chuan Li, Sheyu Li, Yun Zhang, Rui Zheng, Tao Ma, Yi Wang, Miye Su, Na Wu, Ting Liu, Zhiwen Sheng, Xia Li, Nan Liu, Guanjian Huang, Yong Xu, Ting Sun, Xin Tian, Haoming Lipids Health Dis Research BACKGROUND: Diabetes is often accompanied by dyslipidemia. Lipid control is very important in the management of diabetes. There are limited real world data on the lipid control in diabetic inpatients in southwest China. METHODS: An observational study was conducted to assess the characteristics of lipid profiles and lipid control. Diabetic patients from February 2009 to December 2013 at West China Hospital of Sichuan University were identified. RESULTS: A total of 56,784 inpatients were included and 85.9% of them had at least one lipid panel. The proportions of inpatients with optimal low-density lipoprotein cholesterol (LDL-C) level (< 2.59 mmol/L), optimal triglyceride (TG) level (< 1.70 mmol/L), optimal high-density lipoprotein cholesterol (HDL-C) level (men ≥1.04 mmol/L; women ≥1.30 mmol/L) and optimal non-high-density lipoprotein cholesterol (non-HDL-C) level (< 3.37 mmol/L) were 61.1, 64.6, 49.9 and 64.5%, respectively. Only 23.1% of inpatients obtained optimal levels for all the above four lipid parameters. Of diabetic inpatients with ischemic heart disease, the proportions of inpatients with optimal LDL-C level (< 1.81 mmol/L), optimal TG level (< 1.70 mmol/L), optimal HDL-C level (men ≥1.04 mmol/L; women ≥1.30 mmol/L) and optimal non-HDL-C level (< 2.59 mmol/L) were 38.0, 66.3, 48.1 and 48.7%, respectively. Of diabetic inpatients with cerebrovascular disease, the proportions were 28.3, 64.8, 49.9 and 38.1%, respectively. Older people and men were more likely to obtain optimal lipid levels. However, inpatients between 46 and 64 years were least likely to obtain optimal LDL-C levels. CONCLUSIONS: The lipid control of diabetic inpatients in southwest China is worrisome. Individualized strategies of lipid management should be taken to bridge the gap between the recommendations of clinical guidelines and the real situation of clinical practice. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12944-018-0945-8) contains supplementary material, which is available to authorized users. BioMed Central 2019-01-12 /pmc/articles/PMC6330454/ /pubmed/30636643 http://dx.doi.org/10.1186/s12944-018-0945-8 Text en © The Author(s). 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Hou, Qingtao
Yu, Chuan
Li, Sheyu
Li, Yun
Zhang, Rui
Zheng, Tao
Ma, Yi
Wang, Miye
Su, Na
Wu, Ting
Liu, Zhiwen
Sheng, Xia
Li, Nan
Liu, Guanjian
Huang, Yong
Xu, Ting
Sun, Xin
Tian, Haoming
Characteristics of lipid profiles and lipid control in patients with diabetes in a tertiary hospital in Southwest China: an observational study based on electronic medical records
title Characteristics of lipid profiles and lipid control in patients with diabetes in a tertiary hospital in Southwest China: an observational study based on electronic medical records
title_full Characteristics of lipid profiles and lipid control in patients with diabetes in a tertiary hospital in Southwest China: an observational study based on electronic medical records
title_fullStr Characteristics of lipid profiles and lipid control in patients with diabetes in a tertiary hospital in Southwest China: an observational study based on electronic medical records
title_full_unstemmed Characteristics of lipid profiles and lipid control in patients with diabetes in a tertiary hospital in Southwest China: an observational study based on electronic medical records
title_short Characteristics of lipid profiles and lipid control in patients with diabetes in a tertiary hospital in Southwest China: an observational study based on electronic medical records
title_sort characteristics of lipid profiles and lipid control in patients with diabetes in a tertiary hospital in southwest china: an observational study based on electronic medical records
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330454/
https://www.ncbi.nlm.nih.gov/pubmed/30636643
http://dx.doi.org/10.1186/s12944-018-0945-8
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