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Rosiglitazone metformin adduct inhibits hepatocellular carcinoma proliferation via activation of AMPK/p21 pathway

BACKGROUND: Rosiglitazone metformin adduct (RZM) is a novel compound, synthesized from rosiglitazone (Ros) and metformin (Met) combined at a molar mass ratio of 1:1. Met and Ros are widely used together for treating type 2 diabetes to improve drug effectiveness and reduce adverse drug reactions. Rec...

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Detalles Bibliográficos
Autores principales:	Liu, Yuyang, Hu, Xiangnan, Shan, Xuefeng, Chen, Ke, Tang, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330460/ https://www.ncbi.nlm.nih.gov/pubmed/30651718 http://dx.doi.org/10.1186/s12935-019-0732-2

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