Phospholipase Cε plays a crucial role in neutrophilic inflammation accompanying acute lung injury through augmentation of CXC chemokine production from alveolar epithelial cells

BACKGROUND: We have shown that phospholipase Cε (PLCε), an effector of Ras and Rap1 small GTPases, plays pivotal roles in inflammation and inflammation-associated carcinogenesis by augmenting proinflammatory cytokine production from epithelial cells of various organs. The purpose of this study is to...

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Detalles Bibliográficos
Autores principales: Umezawa, Kanoko, Nagano, Tatsuya, Kobayashi, Kazuyuki, Dokuni, Ryota, Katsurada, Masahiro, Yamamoto, Masatsugu, Yoshikawa, Yoko, Kataoka, Tohru, Nishimura, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330467/
https://www.ncbi.nlm.nih.gov/pubmed/30634975
http://dx.doi.org/10.1186/s12931-019-0975-4

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