Cargando…
SOX9 is a dose-dependent metastatic fate determinant in melanoma
BACKGROUND: In this research, we aimed to resolve contradictory results whether SOX9 plays a positive or negative role in melanoma progression and determine whether SOX9 and its closely related member SOX10 share the same or distinct targets in mediating their functions in melanoma. METHODS: Immunof...
Autores principales: | Yang, Xintao, Liang, Rui, Liu, Chunxi, Liu, Jessica Aijia, Cheung, May Pui Lai, Liu, Xuelai, Man, On Ying, Guan, Xin-Yuan, Lung, Hong Lok, Cheung, Martin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330758/ https://www.ncbi.nlm.nih.gov/pubmed/30642390 http://dx.doi.org/10.1186/s13046-018-0998-6 |
Ejemplares similares
-
Nuclear DLC1 exerts oncogenic function through association with FOXK1 for cooperative activation of MMP9 expression in melanoma
por: Yang, Xintao, et al.
Publicado: (2020) -
Fbxo9 functions downstream of Sox10 to determine neuron-glial fate choice in the dorsal root ganglia through Neurog2 destabilization
por: Liu, Jessica Aijia, et al.
Publicado: (2020) -
DEPDC1B Promotes Melanoma Angiogenesis and Metastasis through Sequestration of Ubiquitin Ligase CDC16 to Stabilize Secreted SCUBE3
por: Hu, Feng, et al.
Publicado: (2022) -
Transplanting Human Neural Stem Cells with ≈50% Reduction of SOX9 Gene Dosage Promotes Tissue Repair and Functional Recovery from Severe Spinal Cord Injury
por: Liu, Jessica Aijia, et al.
Publicado: (2023) -
Metabolic nuclear receptors coordinate energy metabolism to regulate Sox9(+) hepatocyte fate
por: Liu, Shenghui, et al.
Publicado: (2021)