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Flash Glucose Monitoring in Subjects with Diabetes on Hemodialysis: A Pilot Study
BACKGROUND: In patients with diabetes related end-stage renal disease (ESRD) on hemodialysis, blood glucose management can be challenging due to the kinetics of glucose and insulin in addition to other factors. The glucose monitoring systems which measure glucose levels continuously may be useful to...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330844/ https://www.ncbi.nlm.nih.gov/pubmed/30766829 http://dx.doi.org/10.4103/ijem.IJEM_520_18 |
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author | Javherani, Rajesh S. Purandare, Vedavati B. Bhatt, Anjali A. Kumaran, Suganthi S. Sayyad, Mehmood G. Unnikrishnan, Ambika G. |
author_facet | Javherani, Rajesh S. Purandare, Vedavati B. Bhatt, Anjali A. Kumaran, Suganthi S. Sayyad, Mehmood G. Unnikrishnan, Ambika G. |
author_sort | Javherani, Rajesh S. |
collection | PubMed |
description | BACKGROUND: In patients with diabetes related end-stage renal disease (ESRD) on hemodialysis, blood glucose management can be challenging due to the kinetics of glucose and insulin in addition to other factors. The glucose monitoring systems which measure glucose levels continuously may be useful to study the glucose profile of patients with diabetes undergoing hemodialysis. Our study is designed to use ambulatory glucose profile to study the glucose pattern – during, before, and after a session of hemodialysis. MATERIALS AND METHODS: Ten patients with type 2 diabetes with ESRD undergoing hemodialysis were recruited. Forty-eight glucose readings were recorded in a 12-h period which included 4 h each prior, during, and after the dialysis session with a flash glucose monitor (FreeStyle Libre-pro). The same 12 h time frame was also monitored on a non-dialysis day. RESULTS: On the day of dialysis, the mean glucose level was significantly lower (P = 0.013) compared to the day without dialysis (95 ± 12.7 mg/dl vs 194 ± 76.8 mg/dl). As compared to the pre-dialysis period, the mean blood glucose levels during dialysis were lower (P = 0.004). As compared to the dialysis period, the mean blood glucose levels in the post-dialysis period were higher but did not reach statistical significance. CONCLUSION: In our study, subjects with type 2 diabetes on hemodialysis had lower glucose levels on the day of dialysis compared to non-dialysis day. Glucose levels showed a fall during hemodialysis and then a rise to higher levels after dialysis. |
format | Online Article Text |
id | pubmed-6330844 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-63308442019-02-14 Flash Glucose Monitoring in Subjects with Diabetes on Hemodialysis: A Pilot Study Javherani, Rajesh S. Purandare, Vedavati B. Bhatt, Anjali A. Kumaran, Suganthi S. Sayyad, Mehmood G. Unnikrishnan, Ambika G. Indian J Endocrinol Metab Brief Communication BACKGROUND: In patients with diabetes related end-stage renal disease (ESRD) on hemodialysis, blood glucose management can be challenging due to the kinetics of glucose and insulin in addition to other factors. The glucose monitoring systems which measure glucose levels continuously may be useful to study the glucose profile of patients with diabetes undergoing hemodialysis. Our study is designed to use ambulatory glucose profile to study the glucose pattern – during, before, and after a session of hemodialysis. MATERIALS AND METHODS: Ten patients with type 2 diabetes with ESRD undergoing hemodialysis were recruited. Forty-eight glucose readings were recorded in a 12-h period which included 4 h each prior, during, and after the dialysis session with a flash glucose monitor (FreeStyle Libre-pro). The same 12 h time frame was also monitored on a non-dialysis day. RESULTS: On the day of dialysis, the mean glucose level was significantly lower (P = 0.013) compared to the day without dialysis (95 ± 12.7 mg/dl vs 194 ± 76.8 mg/dl). As compared to the pre-dialysis period, the mean blood glucose levels during dialysis were lower (P = 0.004). As compared to the dialysis period, the mean blood glucose levels in the post-dialysis period were higher but did not reach statistical significance. CONCLUSION: In our study, subjects with type 2 diabetes on hemodialysis had lower glucose levels on the day of dialysis compared to non-dialysis day. Glucose levels showed a fall during hemodialysis and then a rise to higher levels after dialysis. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6330844/ /pubmed/30766829 http://dx.doi.org/10.4103/ijem.IJEM_520_18 Text en Copyright: © 2018 Indian Journal of Endocrinology and Metabolism http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Brief Communication Javherani, Rajesh S. Purandare, Vedavati B. Bhatt, Anjali A. Kumaran, Suganthi S. Sayyad, Mehmood G. Unnikrishnan, Ambika G. Flash Glucose Monitoring in Subjects with Diabetes on Hemodialysis: A Pilot Study |
title | Flash Glucose Monitoring in Subjects with Diabetes on Hemodialysis: A Pilot Study |
title_full | Flash Glucose Monitoring in Subjects with Diabetes on Hemodialysis: A Pilot Study |
title_fullStr | Flash Glucose Monitoring in Subjects with Diabetes on Hemodialysis: A Pilot Study |
title_full_unstemmed | Flash Glucose Monitoring in Subjects with Diabetes on Hemodialysis: A Pilot Study |
title_short | Flash Glucose Monitoring in Subjects with Diabetes on Hemodialysis: A Pilot Study |
title_sort | flash glucose monitoring in subjects with diabetes on hemodialysis: a pilot study |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330844/ https://www.ncbi.nlm.nih.gov/pubmed/30766829 http://dx.doi.org/10.4103/ijem.IJEM_520_18 |
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