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A two gene-based risk score predicts alcoholic cirrhosis development in males with at-risk alcohol consumption
BACKGROUND: Alcoholic cirrhosis represents 1% of all cause-of-deaths worldwide. Its incidence is higher in males and results from the combination of environmental and genetic factors. Among all the genetic determinants of alcoholic cirrhosis, the patatin-like phospholipase domain protein 3 (PNPLA3)...
Autores principales: | Mancina, Rosellina Margherita, Ferri, Flaminia, Farcomeni, Alessio, Molinaro, Antonio, Maffongelli, Angela, Mischitelli, Monica, Poli, Edoardo, Parlati, Lucia, Burza, Maria Antonella, De Santis, Adriano, Attilia, Fabio, Rotondo, Claudia, Rando, Maria Margherita, Attilia, Maria Luisa, Ceccanti, Mauro, Ginanni Corradini, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330982/ https://www.ncbi.nlm.nih.gov/pubmed/30666147 http://dx.doi.org/10.2147/TACG.S187922 |
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