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The Role of Tripartite Motif Family Proteins in TGF-β Signaling Pathway and Cancer

TGF-β signaling plays a tumor suppressive role in normal and premalignant cells but promotes tumor progression during the late stages of tumor development. The TGF-β signaling pathway is tightly regulated at various levels, including transcriptional and post-translational mechanisms. Ubiquitination...

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Detalles Bibliográficos
Autor principal: Lee, Ho-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Cancer Prevention 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330992/
https://www.ncbi.nlm.nih.gov/pubmed/30671398
http://dx.doi.org/10.15430/JCP.2018.23.4.162