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ATR activated by EB virus facilitates chemotherapy resistance to cisplatin or 5-fluorouracil in human nasopharyngeal carcinoma
PURPOSE: Epstein–Barr virus (EBV) infection is closely associated with nasopharyngeal carcinoma (NPC) and increases the chemotherapy resistance of tumor cells. Although the mechanism by which EBV manipulates ataxia telangiectasia mutation (ATM)-mediated DNA damage response in NPC has been extensivel...
Autores principales: | Zhang, Bo, Cui, Bomiao, Du, Jintao, Shen, Xin, Wang, Kun, Chen, Jiao, Xiao, Liying, Sun, Chongkui, Li, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331066/ https://www.ncbi.nlm.nih.gov/pubmed/30666155 http://dx.doi.org/10.2147/CMAR.S187099 |
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