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Global analysis of N6-methyladenosine functions and its disease association using deep learning and network-based methods
N6-methyladenosine (m(6)A) is the most abundant methylation, existing in >25% of human mRNAs. Exciting recent discoveries indicate the close involvement of m(6)A in regulating many different aspects of mRNA metabolism and diseases like cancer. However, our current knowledge about how m(6)A levels...
Autores principales: | Zhang, Song-Yao, Zhang, Shao-Wu, Fan, Xiao-Nan, Meng, Jia, Chen, Yidong, Gao, Shou-Jiang, Huang, Yufei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331136/ https://www.ncbi.nlm.nih.gov/pubmed/30601803 http://dx.doi.org/10.1371/journal.pcbi.1006663 |
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